Polynucleotide (PN) treatments are gaining popularity as an advanced solution for skin rejuvenation. This guide explores how polynucleotides work, their benefits, potential risks, side effects, and aftercare recommendations.
Definition: Polynucleotide treatments involve injecting bioactive DNA fragments derived from natural sources into the skin to promote regeneration, hydration, and elasticity.
Purpose: To improve skin quality, reduce signs of aging, and support natural repair processes.
Common Brands: Rejuran Healer, Plenhyage, and other PN-based products.
Skin Concerns Addressed:
- Fine lines and wrinkles
- Dull or dehydrated skin
- Acne scars
- Skin elasticity and tone
Mechanism: Polynucleotides are injected into the dermis layer of the skin.
They stimulate collagen production, increase cell turnover, and improve hydration.
The treatment enhances microcirculation and supports tissue repair.
Natural Biocompatibility: Polynucleotides are derived from salmon DNA, which is highly compatible with human skin.
Duration: Results typically develop over several weeks and last 6–12 months, depending on skin type and lifestyle factors.
Risks
Allergic Reactions: Rare but possible, especially for those allergic to fish or seafood.
Infection: As with any injectable treatment, improper hygiene can lead to complications.
Side Effects
Common:
- Redness at the injection sites
- Swelling or slight bruising
- Mild tenderness in treated areas
Rare:
- Formation of small lumps or nodules under the skin
- Inflammatory reactions
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Polynucleotide treatments offer a cutting-edge solution for improving skin quality and addressing signs of aging.
With proper care, they can provide long-lasting, natural-looking results.
Always ensure you work with a qualified practitioner and follow aftercare instructions to maximise the effects.
Polynucleotide (PN) treatments may not be suitable for:
- Pregnant or breastfeeding individuals.
- People with active skin infections, inflammation, or severe acne.
- Those allergic to fish-derived products.
- Anyone with autoimmune conditions affecting the skin.
Actual price will be quoted prior to treatment.
Treatment prices can only be estimated as some treatments require larger amounts to be effective depending on skin condition.
£195 / £550
Includes a course of 3 treatments, each 2-3 weeks apart
Lasts about 4 - 12 months depending on condition
Top up every 4-6 months with a single treatment
Expect a friendly welcome, private 1:1 discussion and advice with an expert and experienced, kind and considerate injector.
Choosing a Qualified Practitioner
Credentials Matter: Choose a qualified medical professional & experienced practitioner specialising in aesthetic injectables.
Research: Look for clinics with good reviews and a reputation for professionalism.
Consultation: Schedule a consultation to discuss your skin goals, medical history, and any concerns.
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